Cognitive and White Matter Tract Differences in MS and Diffuse Neuropsychiatric Systemic Lupus Erythematosus.

B CesarM G DwyerJ L ShucardP PolakNiels P BergslandR H B BenedictB Weinstock-GuttmanD W ShucardR Zivadinov

Published in: AJNR. American journal of neuroradiology (2015)

Patients with MS and neuropsychiatric systemic lupus erythematosus showed widespread WM tract alterations outside overt lesions, though more severe changes were identified in patients with MS. The WM tract changes were associated with cognitive dysfunction in all explored domains only in patients with MS.

Keyphrases

systemic lupus erythematosus
mass spectrometry
multiple sclerosis
ms ms
white matter
disease activity
early onset
rheumatoid arthritis
drug induced