Axial symptoms predict mortality in patients with Parkinson disease and subthalamic stimulation.

Brian LauNiklaus MeierGiulia SerraVirginie CzerneckiMichael SchuepbachSoledad NavarroPhilippe CornuDavid GrabliYves AgidMarie VidailhetCarine KarachiMarie-Laure Welter

Published in: Neurology (2019)

We quantified long-term symptom progression and attenuation of dopaminergic medication and STN-DBS treatment efficacy in patients with PD and linked symptom progression to mortality. Axial disability significantly predicts individual risk of death after surgery, which may be useful for planning therapeutic strategies in PD.

Keyphrases

parkinson disease
deep brain stimulation
cardiovascular events
risk factors
healthcare
emergency department
type diabetes
adverse drug
sleep quality
combination therapy