Cerebrospinal fluid biomarkers of neuroinflammation in children with hydrocephalus and shunt malfunction.
Carolyn A HarrisDiego M MoralesRooshan ArshadJames P McAllisterDavid D LimbrickPublished in: Fluids and barriers of the CNS (2021)
Non-obstructive cases are reported here to accompany significantly higher CSF cytokine and MMP protein levels compared to obstructive cases for IL-10, IL-6, IL-8, MMP-7 and MMP-9. A closer examination of the definition of obstruction and the role neuroinflammation plays in creating shunt obstruction in hydrocephalic patients is suggested.
Keyphrases
- cerebrospinal fluid
- end stage renal disease
- traumatic brain injury
- ejection fraction
- cell migration
- newly diagnosed
- lipopolysaccharide induced
- pulmonary artery
- chronic kidney disease
- cognitive impairment
- young adults
- lps induced
- subarachnoid hemorrhage
- prognostic factors
- cerebral ischemia
- brain injury
- protein protein
- patient reported