CSF biomarkers for predicting phenoconversion in patients with isolated REM sleep behaviour disorder.

Mariana FernandesSilvia MaioPaolo EusebiFabio PlacidiFrancesca IzziMatteo SpanettaClaudia De MasiClementina LupoCarmen CalvelloMarzia NuccetelliSergio BernardiniNicola Biagio MercuriClaudio Liguori

Published in: Sleep (2023)

This study showed that low CSF Aβ42 levels and high BBB alteration may predict the phenoconversion to DLB and PD in iRBD patients, respectively. These findings highlight the possibility to discriminate phenoconversion in iRBD patients through CSF biomarkers, however further studies are needed.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
physical activity
patient reported outcomes
depressive symptoms
patient reported
sleep quality