Naïve regulatory T cells in infancy: Associations with perinatal factors and development of food allergy.
Fiona CollierAnne-Louise PonsonbyMartin O'HelyMimi L K TangRichard SafferyJohn MolloyLawrence E GraySarath RanganathanDavid BurgnerKatrina J AllenSusanne BrixPeter J Vuillerminnull nullPublished in: Allergy (2019)
The proportion of nTreg at birth is a major determinant of the proportion present throughout infancy, highlighting the importance of prenatal immune development. Exposure to the inflammatory stimulus of labour appears to reveal differences in immune function among infants at risk of food allergy.