Perfusate hemoglobin during normothermic liver machine perfusion as biomarker of early allograft dysfunction: A pilot study.
Akinori MaedaGraham StarkeySofia SpanoAnis ChabaGlenn EastwoodOsamu YoshinoMarcos Vinicius PeriniMichael FinkRinaldo BellomoRobert JonesPublished in: Artificial organs (2024)
Perfusate hemoglobin levels decreased during NMP, and lower perfusate hemoglobin levels were associated with a higher incidence of EAD and higher levels of liver injury markers. Maintaining higher hemoglobin levels during NMP may help reduce ischemia-reperfusion injury and prevent or attenuate EAD. Larger prospective studies are needed to validate the findings of this pilot study.