Clinical [ 18 F]FSPG Positron Emission Tomography Imaging Reveals Heterogeneity in Tumor-Associated System x c - Activity.
Amy R SharkeyNorman KoglinErik S MittraSangwon HanGary J R CookTimothy H WitneyPublished in: Cancers (2024)
F]FSPG retention is mediated by the tumor's antioxidant capacity and response to oxidative stress, this heterogeneity may provide important insights into an individual tumor's response or resistance to therapy.