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Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration.

Troy AndersonJulia MoErnesto GagarinDesmarie SherwoodMaria H BlumenkrantzEric MaoGianna LeonHung-Jhen ChenKuo-Chang TsengPeter FabianJ Gage CrumpJoanna Smeeton
Published in: bioRxiv : the preprint server for biology (2023)
Rapid regeneration of the jaw joint ligament in adult zebrafishDedifferentiation of mature ligamentocytes contributes to regenerationscRNAseq reveals dynamic ECM remodeling and immune activation during regenerationRequirement of Legumain for ECM remodeling and ligament healing.
Keyphrases
  • stem cells
  • extracellular matrix
  • anterior cruciate ligament
  • single cell
  • cell therapy
  • childhood cancer
  • mesenchymal stem cells
  • quantum dots