Tofacitinib for acute severe ulcerative colitis: a systematic review.
Casper SteenholdtPernille Dige OvesenJørn BrynskovJakob Benedict SeidelinPublished in: Journal of Crohn's & colitis (2023)
Tofacitinib appears promising for treatment of ASUC with high short-term colectomy-free survival among refractory patients otherwise deemed for colectomy. However, large high-quality studies are needed.
Keyphrases
- ulcerative colitis
- free survival
- rheumatoid arthritis
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- liver failure
- drug induced
- patient reported outcomes
- hepatitis b virus
- acute respiratory distress syndrome
- patient reported
- extracorporeal membrane oxygenation
- mechanical ventilation