The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats.

Adriana Ortega-HernándezErnesto Martínez-MartínezRuben Gómez-GordoNatalia López-AndrésAmaya Fernández-CelisBeatriz Gutiérrrez-MirandaMaria Luisa NietoTeresa AlarcónClaudio AlbaMaria Dulcenombre Gómez-GarréVictoria Cachofeiro

Published in: Antioxidants (Basel, Switzerland) (2020)

These results support an interaction between GM and mitochondrial oxidative stress and its relation with development of cardiac fibrosis, suggesting new approaches in the management of obesity-related cardiometabolic consequences.

Keyphrases

oxidative stress
weight loss
metabolic syndrome
diabetic rats
type diabetes
dna damage
ischemia reperfusion injury
induced apoptosis
insulin resistance
adipose tissue
left ventricular
weight gain
high fat diet induced
heat shock
obese patients
heart failure
endoplasmic reticulum stress
heat stress