Memory B cell-guided extended interval dosing of ocrelizumab in multiple sclerosis.
Delania MengRosaria SaccoGiulio DisantoFausto WidmerSarah Lena Susanna JacoberClaudio GobbiChiara ZeccaPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
memory B cell repopulation led to a great extension of the interval between infusions, with maintained clinical and radiological efficacy. Given the potential advantages in terms of safety and health costs, EID OCR regimens should be further investigated.