The phagocytic state of brain myeloid cells after ischemia revealed by superresolution structured illumination microscopy.

Stefano FumagalliFabio FiordalisoCarlo PeregoAlessandro CorbelliAlessandro MarianiMassimiliano De PaolaMaria-Grazia De Simoni

Published in: Journal of neuroinflammation (2019)

GLCM analysis on SIM dataset quantitatively described different phases of macrophage phagocytic behavior revealing the dynamics of lysosomal movements in the ischemic brain indicating initial active internalization vs. final digestion/autophagy.

Keyphrases

resting state
induced apoptosis
cerebral ischemia
white matter
endoplasmic reticulum stress
cell death
cell cycle arrest
functional connectivity
signaling pathway
high resolution
dendritic cells
acute myeloid leukemia
high throughput
ischemia reperfusion injury
high speed
blood brain barrier
mass spectrometry