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Real-world on-treatment and initial treatment absolute risk differences for dabigatran vs warfarin in older US adults.

Michael A Webster-ClarkTil StürmerJessie K EdwardsCharles PooleRoss J SimpsonJennifer L Lund
Published in: Pharmacoepidemiology and drug safety (2020)
Dabigatran use was associated with lower risks of mortality and ischemic stroke in routine care when older adults stayed on treatment. IT analyses suggested that these benefits may be diminished under real-world patterns of switching and discontinuation.
Keyphrases
  • atrial fibrillation
  • healthcare
  • cardiovascular disease
  • combination therapy
  • cardiovascular events
  • replacement therapy
  • smoking cessation