Login / Signup

CD73-Mediated Immunosuppression Is Linked to a Specific Fibroblast Population That Paves the Way for New Therapy in Breast Cancer.

Ilaria MagagnaNicolas GourdinYann KiefferMonika LicajRana MhaidlyPascale AndreAriane MorelAnne-Vincent SalomonCarine PaturelFatima Mechta-Grigoriou
Published in: Cancers (2021)
Our data support the potential clinical benefit of using both anti-CD73 and immune-checkpoint inhibitors in breast cancer patients for inhibiting CAF-S1-mediated immunosuppression and enhancing anti-tumor immune response.
Keyphrases
  • immune response
  • signaling pathway
  • nk cells
  • big data
  • stem cells
  • machine learning
  • inflammatory response
  • human health
  • artificial intelligence