Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis.

Li-Shuang HouXiao-Pei ZhaiYao-Wen ZhangJie-Hua XingChen LiSi-Yuan ZhouXiao-Hong ZhuBang-Le Zhang

Published in: Liver international : official journal of the International Association for the Study of the Liver (2024)

Construction of HCQ@ROL-LNPs delivery system lays a theoretical and experimental foundation for the treatment of liver fibrosis and promotes the development of clinical therapeutic drugs for liver diseases.

Keyphrases

liver fibrosis
induced apoptosis
oxidative stress
cell death
signaling pathway
endoplasmic reticulum stress
combination therapy
cell proliferation
high density
smoking cessation