Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non-neuroendocrine Small Cell Lung Cancer.
Atsushi FushimiYoshihiro MorimotoSatoshi IshikawaNami YamashitaAtrayee BhattacharyaTatsuaki DaimonHasan RajabiCaining JinMasayuki HagiwaraYota YasumizuZhou LuanWenhao SuoKwok-Kin WongHenry G WithersSong LiuMark D LongDonald W KufePublished in: Molecular cancer research : MCR (2022)
This work uncovers addiction of SCLC cells to MUC1-C, which is a druggable target that could provide new opportunities for advancing SCLC treatment.