Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy.

April C E van GennipNatascha J H BroersKarlien J Ter MeulenBernard CanaudMaarten H L ChristiaansTom CornelisMariëlle A C J GelensMarc M H HermansConstantijn J A M KoningsJeroen B van der NetFrank M van der SandeCasper G SchalkwijkFrank StifftJoris J J M WirtzJeroen P KoomanRemy J H Martens

Published in: PloS one (2019)

Levels of serum biomarkers of ED and LGI were higher in ESRD as compared with controls. In addition, PD initiation and, less convincingly, HD initiation may increase levels of selected serum biomarkers of ED and LGI on top of uremia per se. In contrast to dialysis, several serum biomarkers of ED and LGI markedly declined following kidney transplantation.

Keyphrases

low grade
emergency department
kidney transplantation
high grade
oxidative stress
chronic kidney disease
end stage renal disease
acute kidney injury
peritoneal dialysis
computed tomography