Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma.
Daniel A RauchSydney L OlsonJohn C HardingHemalatha SundaramoorthiYoungsoo KimTianyuan ZhouA Robert MacLeodGrant ChallenLee RatnerPublished in: Retrovirology (2020)
These data support the pursuit of IRF4 as a therapeutic target in ATLL with the use of either ASOs or lenalidomide.
Keyphrases
- dendritic cells
- multiple myeloma
- diffuse large b cell lymphoma
- acute myeloid leukemia
- electronic health record
- bone marrow
- newly diagnosed
- transcription factor
- big data
- stem cell transplantation
- immune response
- chronic lymphocytic leukemia
- childhood cancer
- machine learning
- low dose
- young adults
- artificial intelligence