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Genetic determinants of renal scarring in children with febrile UTI.

Therese RosenbladMagnus LindénInes AmbitePer BrandströmSverker HanssonGabriela Godaly
Published in: Pediatric nephrology (Berlin, Germany) (2024)
In this nationwide study of genetic susceptibility to RS after febrile UTIs in infancy, we identified a profile dominated by mitochondrial polymorphisms. This profile can serve as a predictor of future complications, including RS and recurrent UTIs.
Keyphrases
  • urinary tract infection
  • genome wide
  • oxidative stress
  • young adults
  • copy number
  • chemotherapy induced
  • risk factors
  • weight gain
  • gene expression
  • physical activity
  • weight loss