Proapoptotic and Antiproliferative Effects of the Desert Truffle Terfezia boudieri on Colon Cancer Cell Lines.

Katia SawayaSonia Abou NajemGhada Khawaja Mahmoud Ibrahim Khalil

Published in: Evidence-based complementary and alternative medicine : eCAM (2023)

water extract exerted a cytotoxic effect on colon cancer cells, and blocked colony formation and wound healing potentially through inhibition of proliferation. Mechanistically, these effects are attributed to influence the mitochondrial pathway of apoptosis, proteins involved in cellular proliferation, and the cell cycle.

Keyphrases

cell cycle
oxidative stress
cell proliferation
wound healing
signaling pathway
endoplasmic reticulum stress
cell cycle arrest
cell death