Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes.
Aaron J DeutschPhilip H SchroederRavi MandlaSarah KangFeyza ErenlerJosep M MercaderMiriam S UdlerJose C FlorezLaura N BrennerPublished in: Diabetes care (2023)
Individuals with increased genetic risk of T2D have a higher risk of glucocorticoid-induced hyperglycemia. This finding offers a mechanism for risk stratification as part of a precision approach to medical treatment.
Keyphrases
- type diabetes
- diabetic rats
- high glucose
- end stage renal disease
- ejection fraction
- cardiovascular disease
- oxidative stress
- glycemic control
- newly diagnosed
- healthcare
- drug induced
- prognostic factors
- patient reported outcomes
- genome wide
- metabolic syndrome
- weight loss
- adipose tissue
- patient reported
- copy number
- replacement therapy