Proteomics and UHPLC-DAD-Q/Orbitrap-MS used to identify impurities in andrographolide.

Shuangbing DengYawen ZhangJuan ChenJiaojiao WangJiayi LuoLi FangDifa LiuXiang LvDong QianJing ZhouYuanyuan XieHongyue Ma

Published in: Phytochemical analysis : PCA (2022)

This study will provide useful information on the composition of andrographolide API, which is important for the quality control and clinical safety assurance of API and related prescriptions. Reasonable guidance will also be provided on the necessity of ultrafiltration in the production process of related injections.

Keyphrases

quality control
ms ms
mass spectrometry
simultaneous determination
multiple sclerosis
high resolution
liquid chromatography
high resolution mass spectrometry
tandem mass spectrometry
healthcare
health information