BMSC Alleviates Dry Eye by Inhibiting the ROS-NLRP3-IL-1β Signaling Axis by Reducing Inflammation Levels.

Dandan ZhaoHongxia ZhaoYang HeMeixia Zhang

Published in: Current eye research (2024)

BMSCs inhibit ROS-NLRP3-IL-1β signaling axis, reducing inflammation levels and alleviating dry eye symptoms. These findings provide new ideas and a basis for the treatment of DED and provide an experimental basis for further research on the application value of BMSCs in alleviating DED.

Keyphrases

oxidative stress
dna damage
cell death
reactive oxygen species
nlrp inflammasome
mouse model
sleep quality
combination therapy
replacement therapy