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Different prognostic role of EGFR mutation according to the IASLC histological grade in patients with resected early-stage lung adenocarcinoma.

Tae H HongSoohyun HwangYoon-La ChoiGenehee LeeSehhoon ParkMyung-Ju AhnYoonseo LeeYeong J JeonJunghee LeeSumin ShinSeong Y ParkJong H ChoYong S ChoiJhingook KimYoung M ShimJuhee ChoHong K Kim
Published in: Histopathology (2023)
EGFR mutation status was associated with a risk of recurrence after consideration of the IASLC histological grading, especially in G3 tumours. The results of this study would be useful for developing a new staging system and identifying a subset of patients who may benefit from adjuvant targeted therapy.
Keyphrases
  • early stage
  • small cell lung cancer
  • epidermal growth factor receptor
  • lymph node
  • tyrosine kinase
  • sentinel lymph node
  • radiation therapy
  • prognostic factors