Detection of serum M-protein in acetonitrile pecipitates by MALDI-TOF mass spectrometry: A novel, low-cost methodology.
Nikita MehraGopisetty GopalJayavelu SubramaniSariga DhanasekarArivazhagan RajamanickamJayachandran Perumal KalaiyarasiParathan KarunakaranKrishnarathinam KannanSwaminathan RajaramanThangarajan RajkumarPublished in: Annals of clinical biochemistry (2023)
This study demonstrates the feasibility of qualitatively identifying M-protein without the need for antibody-based immunoenrichment, making the technique cost-effective.