Survivors of infant atypical teratoid/rhabdoid tumors present with severely impaired cognitive functions especially for fluid intelligence and visual processing: data from the German brain tumor studies.
Thomas TraunwieserElena LoosHolger OttensmeierKatharina GastbergerKarolina NemesMartin MynarekBrigitte BisonDaniela KandelsPetra NeumayerAnne Neumann-HolbeckPeggy LüttichKatja BaustKristin Faulstich-RitterRainer JohnAndrea KreischJudyta LandmannEva ManteufelAlexandra NestJenny PrüfeLisa SchubertWalther StammBeate TimmermannJoachim GerssStefan RutkowskiPaul-Gerhardt SchlegelMatthias EyrichAstrid Katharina GnekowMichael Christoph FrühwaldPublished in: Pediatric blood & cancer (2024)
Survivors of infant ATRT experience various late effects in cognition and QoS following multimodal treatment, while infant LGG patients without radiotherapy demonstrated comparable impairments in psychomotor and attention abilities. Early onset and multimodal treatment of rhabdoid tumors require close monitoring of neuropsychological and QoS sequelae.