The End Is in Sight: Current Strategies for the Elimination of HIV Vertical Transmission.
Lanbo YangMary Catherine CambouKarin Nielsen-SainesPublished in: Current HIV/AIDS reports (2023)
Universal third-trimester retesting and partner testing may better identify incident HIV among pregnant patients and result in early initiation of antiretroviral therapy to prevent vertical transmission. The proven safety and efficacy of integrase inhibitors such as dolutegravir may be particularly useful in suppressing viremia in pregnant persons who present late for ART treatment. Pre-exposure prophylaxis (PrEP) during pregnancy may play a role in preventing HIV acquisition; however, its role in preventing vertical transmission is difficult to elucidate. Substantial progress has been made in recent years to eliminate HIV perinatal transmission. Future research hinges upon a multipronged approach to improving HIV detection, risk-stratified treatment strategies, and prevention of primary HIV infection among pregnant persons.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- hiv testing
- men who have sex with men
- pregnant women
- hepatitis c virus
- end stage renal disease
- chronic kidney disease
- type diabetes
- newly diagnosed
- ejection fraction
- current status
- prognostic factors
- south africa