Traditional clinical criteria outperform high-sensitivity C-reactive protein for the screening of hepatic nuclear factor 1 alpha maturity-onset diabetes of the young among young Asians with diabetes.
Chandran SureshJaydutt BhalshankarRashida Farhad VasanwalaYi ZhaoKatharine R OwenDaphne Su-Lyn GardnerPublished in: Therapeutic advances in endocrinology and metabolism (2018)
The use of hs-CRP to guide screening for HNF1A-MODY among Asian young adults with diabetes did not improve the diagnostic yield. Applying a combination of age of onset of diabetes under 25 years and a family history of diabetes alone could guide targeted HNF1A-MODY screening in Asians, with an expected yield of 4% diagnosed with HNF1A-MODY among those screened.