d-glutamate and Gut Microbiota in Alzheimer's Disease.

Chun-Hung ChangChieh-Hsin LinHsien-Yuan Lane

Published in: International journal of molecular sciences (2020)

Gut microbiota and glutamate are potential novel interventions to be developed for dementia. Exploring comprehensive cognitive functions in animal and human trials with glutamate-related NMDAR enhancers are warranted to examine d-glutamate signaling efficacy in gut microbiota in patients with AD and other neurodegenerative dementias.

Keyphrases

endothelial cells
mild cognitive impairment
cognitive decline
physical activity
risk assessment
induced pluripotent stem cells
climate change