Synthesis of [ 18 F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist's perspective.
Torsten KniessJörg ZessinPeter MädingManuela KucharOliver C NeelsKlaus KopkaPublished in: EJNMMI radiopharmacy and chemistry (2023)
F]FMISO, based on in-house prepared FASTlab cassettes, providing the radiotracer for research and preclinical purposes in good radiochemical yields (39%), high radiochemical purities (> 99%) and high molar activity (> 500 GBq/µmol) in a well-priced option.