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Multiomics Profiling Distinguishes Sebaceous Carcinoma from Benign Sebaceous Neoplasms and Provides Insight into the Genetic Evolution of Sebaceous Carcinogenesis.

Gabriel J StarrettBrittany C BaikieBenjamin K StoffHans E GrossniklausInga Van BurenElizabeth G BerryRoberto A NovoaKerri E RiegerKavita Y SarinCharles F LynchMichael C RoyerMary L PiaskowskiIsaac BrownellEmily Y ChuRama GodseSuephy C ChenKelly J YuAlisa M GoldsteinEric A EngelsMichael R Sargen
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
The study findings highlight key diagnostic biomarkers for sebaceous carcinoma and suggest that immunotherapy and modulation of cholesterol biosynthesis could be effective treatment strategies.
Keyphrases
  • genome wide
  • dna methylation
  • cell wall