COVID-19 associated pulmonary aspergillosis (CAPA) in a pregnant woman.
Shruti AgrawalRavi Hari PhulwarePublished in: Autopsy & case reports (2021)
Viral or bacterial co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in the literature. However, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) is limited. COVID-19-associated pulmonary aspergillosis (CAPA) has been seen in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS), which has raised concerns about the worsening disease course of COVID-19 and increasing mortality. We describe a clinical case of CAPA infection and acute respiratory distress syndrome (ARDS) with a deathly outcome in a previously well, non-immunocompromised pregnant woman with intrauterine death of the fetus. Hence, we suggest that clinicians and pathologists keep alerting the possible occurrence of pulmonary aspergillosis in severe/critical COVID-19 patients, and aggressive investigations should be done to rule out the possibility of CAPA so that early treatment can be administrated.
Keyphrases
- sars cov
- acute respiratory distress syndrome
- coronavirus disease
- respiratory syndrome coronavirus
- extracorporeal membrane oxygenation
- mechanical ventilation
- pulmonary hypertension
- systematic review
- pregnant women
- palliative care
- case report
- type diabetes
- intensive care unit
- respiratory failure
- cardiovascular disease
- risk assessment
- early onset
- risk factors
- smoking cessation
- drug induced
- cell wall