Bronchoalveolar Tregs are associated with duration of mechanical ventilation in acute respiratory distress syndrome.

Dustin L NortonAgathe CeppeMiriya K TuneMatthew McCravyThomas DevlinM Bradley DrummondShannon S CarsonBenjamin G VincentRobert S HaganHong DangClaire M DoerschukJason R Mock

Published in: Journal of translational medicine (2020)

Tregs are present in the bronchoalveolar space during ARDS. A greater percentage of CD4+ cells were Tregs in the BAL of FR than SR. Tregs may play a role in the resolution of ARDS, and enhancing their numbers or functions may be a therapeutic target.

Keyphrases

acute respiratory distress syndrome
mechanical ventilation
extracorporeal membrane oxygenation
intensive care unit
respiratory failure
induced apoptosis
cell cycle arrest
cell proliferation
cell death
nk cells