Neurons and Astrocytes in Ventrolateral Periaqueductal Gray Contribute to Restraint Water Immersion Stress-Induced Gastric Mucosal Damage via the ERK1/2 Signaling Pathway.

Wenting GaoZepeng WangHui WangHuimin LiChenxu HuangYangyang ShenXiaoli MaHaiji Sun

Published in: The international journal of neuropsychopharmacology (2022)

These results suggested that activation of VLPAG neurons and astrocytes induced by RWIS through the ERK1/2 signaling pathway may play a critical role in RWIS-induced gastric mucosa damage.

Keyphrases

signaling pathway
stress induced
pi k akt
oxidative stress
spinal cord
induced apoptosis
epithelial mesenchymal transition
diabetic rats
cell proliferation
high glucose
drug induced