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Computational and ADMET Predictions of Novel Compounds as Dual Inhibitors of BuChE and GSK-3β to Combat Alzheimer's Disease.

Saurabh G LondheVinayak WalhekarShenoy K MangalaSuvarna G KiniMarcus Tullius ScottiLuciana ScottiDileep Kumar
Published in: Pharmaceutics (2024)
In summary, our in silico findings have illuminated the potential of our meticulously designed molecules as groundbreaking agents in the fight against Alzheimer's disease, capable of simultaneously inhibiting both GSK-3β and BuChE.
Keyphrases
  • signaling pathway
  • molecular docking
  • cognitive decline
  • pi k akt
  • cell proliferation