PCSK1N as a tumor size marker and an ER stress response protein in corticotroph pituitary adenomas.
Merisa AbusdalKjersti R NormannTuula Anneli NymanKristin Astrid Berland ØysteseArvind Y M SundaramDaniel DahlbergTove LekvaJens BollerslevJens P BergNicoleta C OlarescuPublished in: The Journal of clinical endocrinology and metabolism (2024)
PCSK1N is higher in SCA compared with FCA, and associated with corticotroph cell markers and tumor size. PCSK1N is likely to be part of the adaptive response to ER stress, potentially conferring a survival advantage to the corticotroph tumor cell in conjunction with other proteins.