Metabolic changes in the cingulate gyrus, precuneus, and white matter in anorexia nervosa using multivoxel MR spectroscopy.
Alice RegnaudJosé BotoAntoine KlauserKarl-Olof LövbladMaria Isabel VargasFrancois LazeyrasPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2021)
We observed an increase in choline/creatine in anorexics, possibly reflecting increased cell turnover; a decrease in macromolecules, which was particularly low in the cingulate and precuneus the former being known to be altered in eating disorders; and a decrease in N-acetyl aspartate/creatine considered as a marker of neuronal density and function.
Keyphrases
- anorexia nervosa
- white matter
- functional connectivity
- single cell
- multiple sclerosis
- cell therapy
- high resolution
- bone mineral density
- single molecule
- magnetic resonance
- contrast enhanced
- magnetic resonance imaging
- cerebral ischemia
- mass spectrometry
- blood brain barrier
- body composition
- postmenopausal women
- brain injury