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APOE ɛ4 dose associates with increased brain iron and β-amyloid via blood-brain barrier dysfunction.

Yuto UchidaHirohito KanKeita SakuraiYoshihiko HorimotoEmi HayashiAkihiko IidaNobuyuki OkamuraKenichi OishiNoriyuki Matsukawa
Published in: Journal of neurology, neurosurgery, and psychiatry (2022)
dose is associated with decreased effective brain-waste clearance, such as iron and β-amyloid, through the BBB.
Keyphrases
  • blood brain barrier
  • cerebral ischemia
  • white matter
  • resting state
  • iron deficiency
  • high fat diet
  • subarachnoid hemorrhage
  • brain injury
  • metabolic syndrome
  • risk assessment