Exposure of patients to ionising radiation during lung cancer diagnostic work-up.
Robert Campbell RintoulRachel AthertonKatharine TweedStuart YatesEdwin R ChilversPublished in: Thorax (2017)
We examined the dose of radiation received during diagnosis of lung cancer as this may add to the risk of a second primary cancer. Patients undergoing surgery (n=40) or (chemo)radiotherapy (n=40) received comparable doses (28.6 and 25.8 mSv, respectively), significantly higher than that for supportive care (n=40; 15.1 mSv). The effective dose of radiation received was higher for early stage disease than for those with metastatic disease. The mean lifetime attributable risk of malignancy for those receiving treatment with curative intent in our cohort was 0.059%, and lung-specific risk 0.019%.
Keyphrases
- early stage
- patients undergoing
- radiation induced
- prognostic factors
- end stage renal disease
- newly diagnosed
- minimally invasive
- ejection fraction
- healthcare
- small cell lung cancer
- locally advanced
- palliative care
- combination therapy
- photodynamic therapy
- pain management
- cancer therapy
- lymph node
- coronary artery disease
- surgical site infection
- neoadjuvant chemotherapy
- acute coronary syndrome