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Prevalence of PD-L1 expression in head and neck squamous precancerous lesions: a systematic review and meta-analysis.

Ilaria GirolamiLiron PantanowitzEnrico MunariMaurizio MartiniRiccardo NociniNicola BisiGabriele MolteniDaniele MarchioniClaudio GhimentonMatteo BrunelliAlbino Eccher
Published in: Head & neck (2020)
PD-L1 expression could reflect a point of balance between host immune response and cancer escape ability. High heterogeneity and moderate quality suggest that further studies with larger sample size and more rigorous case selection will allow more precise assessment of PD-L1 expression in HN precancerous lesions.
Keyphrases
  • immune response
  • papillary thyroid
  • risk factors
  • high grade
  • squamous cell
  • single cell
  • low grade
  • toll like receptor
  • squamous cell carcinoma
  • lymph node metastasis
  • inflammatory response