Progression of Atrial Fibrillation after Cryoablation or Drug Therapy.
Jason A GencherMarc W DeyellLaurent MacleGeorge A WellsMatthew BennettVidal EssebagJean ChampagneJean-Francois RouxDerek YungAllan SkanesYaariv KhaykinCarlos MorilloUmjeet JollyPaul NovakEvan LockwoodGuy AmitPaul AngaranJohn L SappStephan WardellSandra LauckJulia Cadrin-TourignySimon KochhäuserAtul Vermanull nullPublished in: The New England journal of medicine (2022)
Initial treatment of paroxysmal atrial fibrillation with catheter cryoballoon ablation was associated with a lower incidence of persistent atrial fibrillation or recurrent atrial tachyarrhythmia over 3 years of follow-up than initial use of antiarrhythmic drugs. (Funded by the Cardiac Arrhythmia Network of Canada and others; EARLY-AF ClinicalTrials.gov number, NCT02825979.).