Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.

Zlata BoiarskaHelena Pérez-PeñaAnne-Catherine AbelPaola MarzulloBeatriz Álvarez-BernadFrancesca BonatoBenedetta SantiniDragos HorvathDaniel Lucena-AgellFrancesca VasileMaurizio SironiJ Fernando DíazAndrea E ProtaStefano PieracciniDaniele Passarella

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2023)

Invited for the cover of this issue are the groups of Professors Passarella and Pieraccini at the University of Milan, in collaboration with some of the members of TubInTrain consortium. The image depicts work with the elements of nature, in particular the destabilising effect of maytansinol (the constellation) on microtubules (the trees). Read the full text of the article at 10.1002/chem.202203431.

Keyphrases

single molecule
deep learning
small molecule
living cells
smoking cessation
fluorescence imaging
nucleic acid
machine learning