Phthalide metabolites produced by mangrove endophytic fungus Pestalotiopsis sp. SAS4.
Jiayin PengPeiwen ChenChuwen LiJuntao LiuYijun SunMingze YangBo DingHongbo HuangYiwen TaoPublished in: Magnetic resonance in chemistry : MRC (2022)
Two new phthalide derivatives (1-2) and four known phthalide compounds (3-6) were purified from the culture of a mangrove endophytic fungus Pestalotiopsis sp. SAS4. Their chemical structures were established by analyses of 1D and 2D nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HR-MS) spectroscopic data. All of these compounds were evaluated in vitro for antibacterial, cytotoxicity, and resistance to hypoxic-ischemic injury activities.
Keyphrases
- magnetic resonance
- high resolution mass spectrometry
- liquid chromatography
- mass spectrometry
- ms ms
- high resolution
- ultra high performance liquid chromatography
- gas chromatography
- multiple sclerosis
- molecular docking
- tandem mass spectrometry
- contrast enhanced
- big data
- silver nanoparticles
- magnetic resonance imaging
- anti inflammatory
- solid state
- computed tomography
- wound healing
- artificial intelligence