Preconception allergen sensitization can induce B10 cells in offspring: a potential main role for maternal IgG.

Marília Garcia de OliveiraLuana de Mendonça OliveiraAline Aparecida de Lima LiraFábio da Ressureição SgnottoAlberto José da Silva DuarteMaria Notomi SatoJefferson Russo Victor

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2017)

Our results reveal that maternal immunization induces allergen-specific B10 cells in offspring and a pivotal role for the IgG repertoire in IL-10 production by murine and human B cells.

Keyphrases

high fat diet
endothelial cells
birth weight
pregnancy outcomes
allergic rhinitis
type diabetes
genome wide
body mass index
single cell
metabolic syndrome
dna methylation
pregnant women
insulin resistance