Resistin directly inhibits bacterial killing in neutrophils.
Lauren MillerKai SingbartlZissis C ChroneosVictor Ruiz-VelascoCharles H LangAnthony S BonaviaPublished in: Intensive care medicine experimental (2019)
Our studies indicate that resistin selectively impairs neutrophil bacterial killing. These findings further support the notion that resistin can mimic cell type-dependent immunosuppressive effects. This is consistent with its putative role in the pathogenesis of bacterial sepsis.