Oroxylin A shows limited antiviral activity towards dengue virus.

Thippayawan RatanakomolSittiruk RoytrakulNitwara WikanDuncan R Smith

Published in: BMC research notes (2022)

value was 201.1 µM, giving a selectivity index (SI) value of 2.66. Accumulation of DENV E protein inside the cell was seen under conditions of post-infection treatment, suggesting that oroxylin A may exert some effects at the virus assembly/egress stages of the replication cycle.

Keyphrases

dengue virus
zika virus
aedes aegypti
single cell
room temperature
binding protein
protein protein