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The increased T helper cells proliferation and inflammatory responses in patients with type 2 diabetes mellitus is suppressed by sitagliptin and vitamin D3 in vitro.

Elham Mahabadi-AshtiyaniVida SheikhShiva BorzoueiIraj SalehiMahdi Alahgholi-Hajibehzad
Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2019)
Sitagliptin plus VitD3 effectively reduces the proliferative T cells response and modulates pro-inflammatory/anti-inflammatory cytokines production.
Keyphrases
  • induced apoptosis
  • signaling pathway
  • cell cycle arrest
  • regulatory t cells
  • dendritic cells
  • cell death
  • pi k akt