Increased extracellular matrix deposition during chondrogenic differentiation of dental pulp stem cells from individuals with neurofibromatosis type 1: an in vitro 2D and 3D study.

Paula Nascimento AlmeidaDeuilton do Nascimento BarbozaEloá Borges LunaMaria Clara de Macena CorreiaRhayra Braga DiasAna Caroline Siquara de SousaMaria Eugenia Leite DuarteMaria Isabel Doria RossiKarin Soares Cunha

Published in: Orphanet journal of rare diseases (2018)

NF1 DPSCs presented increased extracellular matrix deposition during chondrogenic differentiation, which could be related to skeletal changes in individuals with NF1.

Keyphrases

extracellular matrix
signaling pathway
mesenchymal stem cells
lps induced
pi k akt
oxidative stress
nuclear factor
bone marrow