A pyrene-pyridyl nanooligomer as a methoxy-triggered reactive probe for highly specific fluorescence assaying of hypochlorite.
Li ZhangYi XiaoWensheng MaoJiyan HuangHongmei HuangRonghua YangYouyu ZhangXiaoxiao HeKemin WangPublished in: Chemical communications (Cambridge, England) (2022)
A novel pyrene-pyridyl conjugated oligomer (OPP-OMe) was conveniently prepared by one-pot Sonogashira coupling. Intriguingly, it was found that introducing only one methoxy moiety at the 4-pyridyl position can be sufficient for creating an oligomer-based ultrafine reactive fluorescent nanoprobe, i.e. , OPP-OMe NPs ( ca. 2.5 nm in diameter). Spectral analyses and elucidation of the intermediate structure revealed that the methoxy triggered-oxidation, together with nanoaggregation of OPP-OMe NPs, results in rapid, specific and supersensitive sensing of hypochlorite (LOD, 0.3 nM, S/N = 3).
Keyphrases
- living cells
- photodynamic therapy
- quantum dots
- single molecule
- fluorescent probe
- optical coherence tomography
- particulate matter
- single cell
- hydrogen peroxide
- oxide nanoparticles
- magnetic resonance imaging
- nitric oxide
- magnetic resonance
- computed tomography
- optic nerve
- loop mediated isothermal amplification
- energy transfer
- ionic liquid