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Interventional nuclear medicine: "click" chemistry as an in vivo targeting strategy for imaging microspheres and bacteria.

Fijs W B van LeeuwenNikolas DuszenkoD M van WilligenA W HensbergenTessa BuckleDaphne D D RietbergenMeta RoestenbergFijs W B van Leeuwen
Published in: Biomaterials science (2021)
Copper-free click chemistry between a DBCO moiety and Cy5-N3-functionalized microspheres or bacterial entities in the liver can be used to realize in vivo imaging and targeting.
Keyphrases
  • high resolution
  • cancer therapy
  • drug discovery
  • mass spectrometry
  • drug delivery
  • photodynamic therapy
  • fluorescence imaging